| abstract |
The present invention provides compounds of general formula (I), or pharmaceutically acceptable esters of such compounds, and pharmaceutically acceptable salts thereof: Embedded image here, R 1 represents a hydrogen atom, an alkyl group, etc .; R 2 represents a hydrogen atom, a halogen atom, etc .; R 3 represents an alkyl group, etc .; R 4 represents an aryl group, etc .; A represents an aryl 1 represents 1 etc .; B represents alkylene or the like; X represents NH or the like. These compounds are useful for the treatment of medical conditions mediated by prostaglandins such as pain, fever or inflammation. The present invention also provides a pharmaceutical composition comprising the above compound. |