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publicationDate 2005-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2005530528-A
titleOfInvention Biomedical polymers having branched polyethylene oxide end groups and their use in biomedical devices
abstract The biopolymer has a substantially linear base polymer; and branched polyethylene oxide covalently bonded to the base polymer as surface active end groups. Branched polyethylene oxide has at least 2, more particularly at least 4, even more particularly at least 6 branches. Suitable base polymers include epoxies, polyurethanes, polyurethane copolymers, fluoropolymers, polyolefins and silicone rubbers. The bioactive agent can be bound to the branched polyethylene oxide. Suitable bioactive agents include microbial peptide agents, detergents, non-steroidal anti-inflammatory agents, cations, amine-containing organosilicones, diphosphonates, fatty acids, fatty acid salts, heparin and glucocorticosteroids. The biopolymer can be used as a casing for a medical unit of an implantable medical device such as a pacemaker. In that case, the casing at least partially seals the medical unit.
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