| abstract |
The present invention relates to methods and compositions for treating or preventing catabolism and promoting anabolism in mammals undergoing metabolic stress. The method comprises methyl donation selected from the group consisting of L-serine, methionine, choline, phosphatidylcholine, betaine, dimethylglycine, sarcosine, methylated folic acid, S-adenosylmethionine, thymidine triphosphate, adenosine triphosphate. Administering to the mammal a composition comprising a body and optionally a methyl receptor selected from the group consisting of L-glycine, ethanolamine, phosphatidylethanolamine, folic acid, ribose. Here, the total amount of methyl donor delivered by the method is at least 0.18 mmol / kg body weight / day above that of the methyl acceptor. |