abstract |
The present invention relates to 3-substituted amino-1H- for use in the treatment of diseases associated with allergy, asthma, rhinitis, dermatitis, B cell lymphoma, tumors and bacteria, rhinovirus or respiratory syncytial virus (RSV) infection. Indole-2-carboxylic acid and 3-substituted aminobenzothiophene-2-carboxylic acid derivatives are disclosed and claimed. The compound of the present invention can regulate T helper cells (Th) and Th1 / Th2, thereby inhibiting interleukin-4 (IL-4) message transcription, IL-4 release or IL-4 production. I understand this time. |