| abstract |
A membrane protein expressed by mast cells that is highly expressed in human mast cells and lungs compared to in brain, heart, kidney, liver, trachea and similar tissues. The protein is a transmembrane protein involved in the regulation of mast cell and lung tissue function, including mast cell degranulation. A preferred protein is a 187 amino acid transmembrane protein (SEQ ID NO: 2) having an intracellular region of amino acids 1 to 82, a transmembrane region of amino acids 83 to 105, and an extracellular region of amino acids 106 to 187. |