| abstract |
The present invention is a process for measuring the level of expression of a gene in an experimental sample obtained from a cell having a deficient level of a component of the NF-κB pathway, obtained from a wild type cell having a level of a component of the biological pathway Measuring the level of expression of the gene in a control sample, and selecting a gene having a level of expression modulated in the experimental sample relative to the wild-type sample. A method for identifying a gene related to a pathway is provided. The present invention also provides a method for treating inflammation-related diseases by modulating the activity of IKKα. |