abstract |
Structure I, including pharmaceutically acceptable salts and stereoisomers thereof, wherein A, A ′, B, X, Y, R 2 , R 3 , R 4 and R 5 are as defined herein. Compound). Such compounds have benefits across a wide range of applications, including use as diagnostic and therapeutic agents. In particular, the compounds of the present invention and pharmaceutical compositions containing such compounds are tryptase antagonists. |