| abstract |
Covalently lipidated oligonucleotides containing CpG dinucleotide units, or analogs thereof, alone or in combination with immunogens and / or non-immunological agents, for protection against diseases caused by cancer cells or pathogens It can be used as an immunostimulatory drug. Of particular interest are lipidated oligonucleotides with special backbones, lipidated oligonucleotides having less than 8 nucleotides, and lipidated oligonucleotides comprising multiple CpG dinucleotide-containing segments joined by long internucleoside linkages. These compounds are also novel per se. |