http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005526058-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 |
| filingDate | 2003-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2005-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2005526058-A |
| titleOfInvention | Heterocyclic amide derivatives as inhibitors of glycogen phosphorylase |
| abstract | Formula (I) wherein X is N or CH; R 4 and R 5 together are —S—C (R 6 ) ═C (R 7 ) — or —C (R 7 ) ═C (R 6 ) —S—; R 6 and R 7 are independently selected from, for example, hydrogen, halo, and C 1-4 alkyl; A is phenylene or heteroarylene; n Is 0, 1 or 2; R 1 is, for example, halo, nitro, cyano, hydroxy, carboxy; R 2 is hydrogen, hydroxy, or carboxy; R 3 is, for example, hydrogen, hydroxy, Selected from aryl, and C 1-4 alkyl (optionally substituted with 1 or 2 R 8 groups); R 8 is, for example, hydroxy, —COCOOR 9 , —C (O) N (R 9 ) ( R 10 ), —NHC (O) R 9 , (R 9 ) (R 10 ) N— And is selected from -COOR 9; R 9 and R 10, for example, hydrogen, hydroxy, selected from (as optionally substituted by R 13 of one or 2) C 1-4 alkyl; R 13 is hydroxy, A amide selected from halo, trihalomethyl and C 1-4 alkoxy], or a pharmaceutically acceptable salt or prodrug thereof, possesses glycogen phosphorylase inhibitory activity and thus increased glycogen phosphorylase Useful for the treatment of pathologies associated with activity. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018039784-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10259825-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10947237-B2 |
| priorityDate | 2002-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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