http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005525422-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-657181 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6571 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 |
| filingDate | 2003-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2005-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2005525422-A |
| titleOfInvention | Preparation of cyclic prodrugs of PMEA and PMPA |
| abstract | Formula I: [Chemical 1] [Where: M and V are in cis with each other, MPO 3 H 2 is a phosphonic acid selected from the group consisting of 9- (2-phosphonylmethoxyethyl) adenine and (R) -9- (2-phosphonylmethoxypropyl) adenine; V is phenyl optionally substituted with one to two substituents selected from the group consisting of fluoro, chloro and bromo] A method for producing a compound represented by A method for coupling chiral 1-phenylpropane-1,3-diol (wherein the phenyl may be substituted) with MPOCl 2 or its N-6 substituted analog is described. In addition, methods and salt forms are described that allow isolation and purification of the desired isomer. |
| priorityDate | 2002-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.