| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0478
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F13-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0487
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-20 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01T1-161
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F13-00 |
| filingDate |
2003-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2005-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2005523941-A |
| titleOfInvention |
Tumor imaging compounds |
| abstract |
The present invention provides novel amino acid compounds for use in the detection and evaluation of brain and body tumors. These compounds combine the advantageous features of α-aminoisobutyric acid analogs, which are characterized by their long uptake in tumors using their fast uptake and the properties of halogen substituents, including some useful halogen isotopes. Is. The amino acid compounds disclosed herein have high specificity at the target site when administered in vivo, and preferred amino acid compounds include [ 18 F] FAMP and [ 18 F] N-MeFAMP. It is done. The invention further features a pharmaceutical composition comprising an α-amino acid moiety attached to either a four-membered, five-membered or six-membered carbon chain. Labeled amino acid compounds are useful as imaging agents in the detection and / or monitoring of tumors in subjects by positron emission tomography and single photon emission computed tomography. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019536735-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7036802-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021504472-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7252653-B2 |
| priorityDate |
2002-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |