abstract |
The expandable medical device comprises a plurality of elongated struts that are coupled together to form a generally cylindrical device that is expandable from a cylindrical shape having a first diameter to a cylindrical shape having a second diameter. Have. At least one of the plurality of struts includes at least one opening that extends at least partially in the thickness direction of the strut. The beneficial agent is loaded into the stent opening to achieve the kinetics of releasing the drug at the required time. Alternatively, the beneficial drug is loaded into a shape configured to achieve the required drug delivery profile. Various delivery profiles include zero order, pulsation, increase, decrease, sinusoid function, and other delivery profiles. |