| abstract |
The present invention relates to a method of modulating the differentiation of mammalian stem cells or progenitor cells. The methods of the invention can be used to regulate and control the differentiation and maturation of mammalian, particularly human, stem cells into specific cells and tissue lineages. The methods of the present invention modulate the differentiation of stem or progenitor cell populations into specific cells and tissue lineages, particularly the differentiation of embryonic-like stem cells derived from postpartum placenta, or early It relates to the use of certain small organic molecules for the differentiation of progenitor cells into the granulocyte lineage. Finally, the present invention relates to the use of such differentiated stem cells or progenitor cells in transplantation and other medical procedures. |