abstract |
Heterocritic analogs of class I epitopes are the 3rd and / or 4th and / or 5th and / or 6th and / or 7th and / or 8th and / or 9th and / or 10th of these epitopes Prepared by making conservative, semi-conservative or non-conservative amino acid substitutions at the positions. This analog is useful to elicit an immune response against the corresponding wild type epitope. |