abstract |
Compound of formula (I): [Chemical 1] (Wherein R 1 , R 2 , R 3 , R 4 , R 5 and p are as defined herein) and pharmaceutically acceptable salts and in vivo hydrolysable esters thereof are described. Also described are their methods of manufacture and their use as medicaments, particularly as medicaments for producing cell cycle inhibition (cell growth inhibition) effects in warm-blooded animals such as humans. |