Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2299-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
filingDate |
2003-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2005-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2005518804-A |
titleOfInvention |
Cold shock-induced expression and production of heterologous polypeptides |
abstract |
The present invention relates to a DNA molecule or vector that can be used to produce a heterologous polypeptide under conditions that induce a cold shock response in the host cell and a host cell containing the DNA or vector. DNA molecules and vectors include a nucleotide sequence encoding a heterologous polypeptide and a promoter and 5'-UTR from a cold shock inducible gene that directs its expression. Furthermore, an AT-rich sequence that enhances translation under cold shock inducible conditions is in the coding sequence of the heterologous polypeptide or in an additional element inserted between the coding sequence and the cold shock inducible promoter and 5′-UTR. Exists in either. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009273432-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007275010-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009531032-A |
priorityDate |
2002-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |