| abstract |
The present invention relates to a method of treating unstable or overactive bladder, comprising administering to a patient in need of such treatment a pharmaceutically effective amount of an antimuscarinic agent and an estrogen agonist. The antimuscarinic agent is preferably tolterodine or a tolterodine related compound. The invention also relates to the use of pharmaceutical formulations containing antimuscarinic agents, estrogen agonists and pharmaceutical diluents, and combinations thereof for the manufacture of therapeutic formulations for treating unstable or overactive bladder. |