| abstract |
The present invention provides a compound of formula (I) useful as an agonist or antagonist of melanocortin receptor. [Chemical 1] [Wherein R 1 , R 2 and R 4 are ring-containing groups, and R 3 is H, alkyl, alkenyl or alkynyl] Is directed to a novel 1,2,4-thiadiazole-2-ium derivative represented by: More particularly, the compounds of the present invention are useful for the treatment of metabolic disorders, CNS disorders and dermatological disorders. |