| abstract |
Novel receptors referred to herein as “TACIs” and “BR3”, agonists and antagonists thereof, and TNFR family and TNF, eg, tumor necrosis factor (TNF) and TNFR related molecules such as TALL-1, APRIL, TACI and BCMA Methods of using TACIs and BR3, and agonists or antagonists thereof, to modulate the activity of family members are provided. Further provided are methods for in vitro, in situ, and / or in vivo diagnosis and / or treatment of pathological conditions or mammalian cells associated with such TNF and TNFR related molecules. |