| abstract |
The present invention relates to α-oxidized or α-thiolated phenethylamide derivatives of the general formula I: [Chemical 1] For those comprising optical isomers and mixtures of such isomers: wherein A means optionally substituted aryl or optionally substituted heteroaryl; X is oxygen or sulfur Y is oxygen or sulfur; R 1 is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, haloalkyl, haloalkenyl, haloalkynyl or halocycloalkyl; R 2 is hydrogen, alkyl, alkenyl, Alkynyl, cycloalkyl, cycloalkyl-alkyl, alkoxy-alkyl, alkoxy-alkenyl, alkoxy-alkynyl, where all alkyl-, alkenyl-, alkynyl-, or cycloalkyl-groups may be optionally substituted with halogen Or optionally substituted aryl-alkyl, optionally substituted aryl- Alkenyl, optionally substituted aryl - alkynyl, or optionally substituted aryloxy - is alkyl; R 3 is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkyl - alkyl, alkoxy - alkyl, alkoxy - alkenyl , Alkoxy-alkynyl, wherein all alkyl-, alkenyl-, alkynyl-, or cycloalkyl- groups may be optionally substituted with halogen; or optionally substituted aryl-alkyl, optionally substituted Optionally substituted arylalkenyl, optionally substituted aryl-alkynyl, optionally substituted aryloxy-alkyl, optionally substituted heteroaryl-alkyl, optionally substituted heteroaryl-alkenyl, or optionally substituted heteroaryl - alkynyl; R 4 is Alkyl, alkenyl, alkynyl, alkoxy-alkyl, alkoxy, alkenyloxy, alkynyloxy, alkylthio, alkanoyl, alkylamino, dialkylamino, alkoxycarbonyl, where all alkyl-, alkenyl- or alkynyl-groups are optionally halogenated Or is halogen, cyano, nitro, amino, formyl or carboxyl; R 5 is hydrogen, alkyl, alkenyl or alkynyl; n is an integer 0, 1, 2, 3 or 4 B 1 represents a bridge member (CR 10 R 11 ) q- or-(CHR 10 R 11 ) r -Z- (CR 12 R 13 ) S , where q is an integer 2, 3 or 4 R is an integer 0, 1, 2, 3; s is an integer 1, 2, or 3 provided that (r + s) is either 1, 2 or 3, and Z is , -0-, -S-, -SO-, -SO 2- , -NR 6- , -CO-, -OOC-, -COO-, -NR 6 -CO or -CO-NR 6 ; R 6 is hydrogen or alkyl; R 10 , R 11 , R 12 and R 13 are Independently hydrogen or alkyl; and B 2 is an alkylene bridge. ). These compounds have useful plant defense properties and can be advantageously utilized in agricultural practice for controlling or protecting against the phytopathogenic fungi, especially fungal plants. |