http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005508988-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-343 |
| filingDate | 2002-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2005-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2005508988-A |
| titleOfInvention | New mandelate salts of substituted tetracyclic tetrahydrofuran derivatives. |
| abstract | [Chemical 1] The object of the present invention is a novel mandelate salt of the substituted tetracyclic tetrahydrofuran derivative of formula (I), its N -oxide form and stereochemical isomers, wherein R 1 and R 2 are each independently Hydrogen or C 1-6 alkyl, and R 3 and R 4 are each independently hydrogen or halogen. In the above definition, C 1-6 alkyl is a straight chain having 1-6 carbon atoms such as, for example, methyl, ethyl, propyl, butyl, 1-methylpropyl, 1,1-dimethylethyl, pentyl and hexyl and It is defined as a branched saturated hydrocarbon group. The new mandelate salt is not light-sensitive and is more stable at room temperature, elevated temperature and relative humid and aqueous media than prior art salts. Also disclosed is a pharmaceutical composition comprising the mandelate salt of the present invention, the mandelate salt of the present invention for use as a medicament, the preparation of the mandelate salt of the present invention, and CNS disorders, cardiovascular The use of the mandelate of the invention and the pharmaceutical composition comprising the mandelate of the invention for the treatment or prevention of disorders and gastrointestinal disorders. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005511691-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016530311-A |
| priorityDate | 2001-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 91.