http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005507076-A

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54353
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-531
filingDate 2002-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2005-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2005507076-A
titleOfInvention Immobilization of biological molecules
abstract The present invention provides a system for immobilizing biological molecules to a solid support having available amino groups using two steps. In the first step, a nucleophilic substitution reaction occurs such that the available amino group displaces the first leaving group of the activating compound to form an activated support. In the second step, the activated support reacts with a biological molecule to produce a compound of formula (I): In formula (I), S is a solid support and X is preferably selected from the group consisting of the following formulas (i), (ii), (iii) and (iv), wherein R is about Selected from the group consisting of alkyl groups, allyl groups and OR 1 having 18 or fewer carbon atoms, R 1 is selected from the group consisting of alkyl groups and allyl groups having about 18 or fewer carbon atoms; X 1 is selected from the group consisting of NH, oxygen and sulfur, and B is a biological molecule.
priorityDate 2001-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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