| abstract |
Organized mobile multicomponent conjugates (OMMC) and methods of use thereof for enhancing the binding of compounds that bind weakly to a target. A layered structure containing at least two binding compounds assembles under conditions in which the binding compound self-regulates in or on the layered structure and is capable of binding to a complementary affinity site on the target with enhanced affinity. Form a common group. Each binding compound binds to the layered surface and can be linked with a linker. The OMMC can contain an effector molecule, such as a diagnostic or therapeutic agent, for administration to a patient diagnosed or treated using the effector molecule. |