| abstract |
The present invention relates to a cultured stratified cartilage tissue comprising a tissue engineered adherent cartilage construct containing two or more cartilage layers, wherein each cartilage layer is adjacent to the surface area of the natural cartilage, of the natural cartilage. Chondrogenic cells having a chondrogenic phenotype corresponding to chondrocytes present in the intermediate transition zone, deep zone of natural cartilage, or calcified cartilage zone of natural cartilage. |