| abstract |
The present invention relates to compositions and methods for selectively expressing polypeptides within membrane vesicles. The invention also relates to genetic constructs and recombinant cells suitable for the production of such membrane vesicles. The invention also relates to functionalized membrane vesicles and methods of producing antibodies, methods of inducing or controlling immune responses, and methods of screening or identifying binding partners. More specifically, the invention uses lactadhedrin or a portion thereof to selectively express a polypeptide in membrane vesicles of natural or synthetic origin. The present invention can be used in the experimental, research, therapeutic, preventive or diagnostic fields. |