| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6803 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F17-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K- |
| filingDate |
2002-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2005-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2005503380-A |
| titleOfInvention |
Methods for detecting cysteine variants and ligands that bind to biological molecules |
| abstract |
The present invention relates generally to variants of target biological molecules ("TBMs"), as well as methods of making them and methods of using them to identify ligands for TBMs. More particularly, the present invention relates to individual variants TBM and sets of variants TBM, each of which is a modified version of a protein of interest in which a thiol is introduced at or near the site of interest. Represent. TBM ligands are identified in part by the formation of covalent bonds between potential ligands and reactive thiols on the TBM. |
| priorityDate |
2001-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |