http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005503363-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D313-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D313-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 |
| filingDate | 2002-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2005-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2005503363-A |
| titleOfInvention | Eurotinone and its derivatives, process for producing them and use thereof |
| abstract | The present invention relates to general formula (I) [Chemical 1] [Wherein R (1), R (2), R (3), R (4) independently represent hydrogen or an alkyl group)]. The compounds of formula (I) are inhibitors of KDR-kinase, have an anti-angiogenic effect and are suitable for the prevention and / or treatment of malignant diseases. The compound of formula (I) can be obtained by culturing the microorganism Eurotium echinulatum Delacroix (DSM 13872) or by chemically derivatizing the compound obtained after culturing the microorganism. Can do. The present invention also provides a method for producing a compound of formula (I), a medicament for treating a malignant disease and a disease that can be treated by inhibiting KDR-kinase, and at least one formula It also relates to the use of the above compounds for pharmaceutical formulations containing a compound of (I). |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010213686-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010095399-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012231679-A |
| priorityDate | 2001-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 85.