| abstract |
The present invention is a method and product for FGF dimerization. In particular, compositions of FGF dimers are provided. Also provided are methods of using those compositions, including therapeutic uses. For some aspects, the present invention provides a modified FGF dimer pharmaceutical composition comprising two FGF monomers linked together, wherein the dimer is at least one from a natural FGF dimer. Modifications and pharmaceutically acceptable carriers. Another aspect of the present invention is a composition of stabilized modified FGF dimers comprising two FGF monomers linked together, wherein the dimer exhibits at least one modification from a native FGF dimer. Including. |