| abstract |
Disclosed are compounds of formula (I), prodrugs thereof, or pharmaceutically acceptable salts or solvates of the compounds or prodrugs, which are useful as inhibitors of type 3 17β-hydroxysteroid dehydrogenase. The invention also relates to pharmaceutical compositions containing this compound and the use of this compound to treat or prevent androgen-dependent diseases. Androgen-dependent diseases to which the present invention relates include prostate cancer, benign prostatic hypertrophy, pressure ulcers, seborrhea, hirsutism, androgenic hair loss, premature sexual maturity, decreased adrenal function, and polycystic ovary syndrome It is not limited to. |