http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005501028-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-16 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B55-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-02 |
filingDate | 2002-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2005-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2005501028-A |
titleOfInvention | Kinetic separation of an intermediate useful for the production of benazepril and its analogs. |
abstract | The present invention relates to a method for preparing angiotensin converting enzyme (ACE) inhibitors useful in the treatment of hypertension, chronic heart failure, and progressive chronic renal failure. In particular, the method of the present invention is useful for mass production of 3-[(1 '-(alkoxycarbonyl) -3'-phenylpropyl) amino] -2-oxo- [1] -benzazepine and its derivatives. In particular, the present invention is the desired form for the production of benazepril from a single diastereomeric form R, S by using a method of epimerization and kinetic separation of a class of chemical compounds. It represents a unique method of converting an intermediate compound in the synthesis of benazepril to another diastereomeric form S, S. |
priorityDate | 2001-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.