abstract |
The present invention provides compounds of formula I: (Where X, R 1 , R 2 , R 3 , R N , R 20 , and R C are as described in the specification) Of the substituted alcohol compound. These compounds are useful for the treatment or prevention of Alzheimer's disease. More specifically, the present invention has the ability to inhibit beta-secretase, an enzyme that cleaves amyloid precursor protein to produce amyloid beta peptide (Abeta; the main component of amyloid plaques found in the brains of Alzheimer's disease patients). It is related with the compound which has. |