abstract |
The present invention relates to inhibitors (ia)-(id) of p38, a mammalian protein kinase involved in cell proliferation, cell death and response to extracellular stimuli. The compounds of the invention are described herein. The invention also relates to methods for producing these inhibitors. The present invention also provides pharmaceutical compositions comprising the inhibitors of the present invention and methods of using those compositions in the treatment and prevention of various disorders. All substituents are shown in claim 1. |