| abstract |
3-Benzamide-2-hydroxycarboxylic acid represented by 3-benzamido-2-hydroxy-3-phenylpropionic acid or a salt thereof with high yield and high optical purity by a safe and suitable method for industrialization A method of manufacturing the same is provided. An optically active 4- (N-protected amino) -1-alkene-3-ol represented by the following formula is produced through a four-step process, and 3-benzamide-2-ol is further produced from the compound. Hydroxycarboxylic acid or a salt thereof is produced. (In the formula, R represents an alkyl group, an alkenyl group, etc., X represents a protecting group for a nitrogen functional group, and Z represents an acyl group) [Selection figure] None |