http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005300516-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69b4de7d64ebafc368b849bca94eab18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate | 2004-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c1754ef88b29cf4ff4fa06ad2265c8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3cc16509767de9ce518bc46c239b0b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f0be15d1ef9654613dff57f6b721d8b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e23063f5bb6994d3555e78553c439d09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6eaa7294cceb789d73fa5af57209126f |
| publicationDate | 2005-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2005300516-A |
| titleOfInvention | Drug screening method using Alzheimer's disease model animal |
| abstract | The present invention provides means that can be used to develop preventive, ameliorating, or therapeutic means for Alzheimer's disease (AD), thereby enabling prevention, amelioration, or treatment of AD. A method for screening a prophylactic, ameliorating, or therapeutic agent for AD, comprising using a osteopetrosis (op / op) mouse that causes Aβ deposition in the brain by 30 days after birth; inhibition of Aβ deposition; A method for screening an agent, a fibrous plaque formation inhibitor or a neuronal loss inhibitor; a prophylactic agent, an improving agent or a therapeutic agent for AD obtained by the screening method, including M-CSF, G-CSF and / or VEGF; Aβ deposition inhibitor, fibrous plaque formation inhibitor or neuronal loss inhibitor containing M-CSF, G-CSF and / or VEGF, etc .; AD prevention method, improvement method or treatment method characterized by using the above-mentioned agent A method for inhibiting Aβ deposition, a method for inhibiting fibrous plaque formation, or a method for inhibiting neuronal loss, which comprises using the above-mentioned agent. [Selection figure] None |
| priorityDate | 2004-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.