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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-96
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filingDate 2004-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e90067784deafc1303efd8773e26c44d
publicationDate 2005-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2005270007-A
titleOfInvention Stabilized enzyme, method for producing the same, and material synthesis method using the stabilized enzyme
abstract PROBLEM TO BE SOLVED: To provide a stabilized enzyme that has excellent reaction rate and optical selectivity, can be left at room temperature, and retains activity even in an organic solvent, and a method for stabilizing the enzyme. In addition, the present invention provides a material synthesis method using an enzyme reaction excellent in reaction rate and optical selectivity. By adding an ionic liquid to an enzyme buffer solution and then freeze-drying, the enzyme is coated with the ionic liquid, and becomes a stabilized enzyme that can be left at room temperature and retains activity even in an organic solvent. By using this stabilized enzyme in a material synthesis reaction, a material synthesis method excellent in reaction rate and optical selectivity can be provided. Among ionic liquids, it is particularly effective to add Brij-IL to the enzyme reaction solution at a ratio of 10 mol% or less with respect to the substrate alcohol. [Selection figure] None
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