| abstract |
The present invention provides a β-amyloid toxicity alleviating agent having a large effect of suppressing the progression of Alzheimer's disease and having no safety problem. The present invention includes an actomyosin degradation product as an active ingredient. In particular, an actomyosin degradation product uses actomyosin extracted from animal muscles, particularly porcine skeletal muscle, and is used as papain, phytin, pepsin, trypsin. , Α-chymotrypsin, thermolysin, pronase, bromelain and the like were obtained by enzymatic degradation. In particular, a product obtained by decomposing actomyosin in water having a pH of 3 to 12 in the presence of papain and further fractionating a molecular weight of 10,000 or less from the decomposition product. [Selection] Figure 1 |