| abstract |
PROBLEM TO BE SOLVED: To provide a heterocyclic amidine compound having anti-inflammatory and analgesic activity. The heterocyclic amidine compound of the present invention is represented by the following formula (I). [Chemical 1] Wherein G 1 and G 2 are each independently selected from hydrogen, halogen, hydroxyl, C 1 -C 4 alkoxy, C 1 -C 4 alkyl, and amidine substituents of formula Q below, provided that 2 Only one of the two substituents G 1 or G 2 is an amidine substituent of formula Q, where W, Y and X are combined together to contain 9 or 10 members containing up to 2 heteroatoms in the same ring Forming a bicyclic heteroaromatic derivative of; and Z is an aryl or heteroaryl group, a linear or branched C 1 -C 6 alkyl or alkenyl group, or a C 1 -C 4 alkyl-aryl group or a C 1 -C 4 alkyl-heteroaryl group] [Selection figure] None |