abstract |
PROBLEM TO BE SOLVED: To provide a compound for treating or preventing brain damage caused by diseases such as cerebrovascular disorder, brain degenerative disease, demyelinating disease and the like, and a screening method thereof. The object of the present invention can be solved by a pharmaceutical composition comprising an inhibitor of a hematopoietic prostaglandin D synthase as an active ingredient. In addition, these hematopoietic prostaglandin D synthase overexpressing transgenic mice can be easily screened for compounds having these medicinal effects. [Selection figure] None |