| abstract |
An aminopeptidase having properties sufficient for application to a catalyst or the like is provided. SOLUTION: Optimal reaction pH 7.5 to 10.5, L-Leu-pNA, L-Phe-pNA, L-Met-pNA, L-Lys-pNA, L-Ala-pNA and L-Pro-pNA Streptomyces, an aminopeptidase that exhibits hydrolytic activity on water, an optimum reaction temperature of about 75 ° C., thermal stability of 50% heat inactivation temperature of about 78 ° C., and calcium ions that have substantially no effect on catalytic activity. Specific base sequence derived from or a mutant nucleic acid thereof, recombinant aminopeptidase, production method thereof, carrier for expression thereof, transformed cell retaining the nucleic acid, probe for detecting the nucleic acid, nucleic acid or part thereof A primer pair for amplifying a protein, a method for searching for an aminopeptidase using the probe and / or the primer pair, and the aminopeptidase or the recombination Antibody or fragment thereof to Minopepuchidaze. [Selection figure] None |