http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005204535-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7d2b340ec52e16006c03624f76998e52 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2004-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a53062be263f6dcc121d2fe7dce5b51c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af77f5fb704cf3f4f7663d1db3a43c1f |
publicationDate | 2005-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2005204535-A |
titleOfInvention | Screening method for anticancer drug |
abstract | PROBLEM TO BE SOLVED: To provide a method for screening a new anticancer agent or an anticancer activity enhancer by identifying an efflux pump that excretes an anticancer agent from cancer cells and searching for a substance that inhibits the efflux pump. SOLUTION: A method for screening an anticancer agent or a sensitivity enhancer of an anticancer agent using a TETRAN gene having a pumping function for discharging an anticancer agent from cancer cells, specifically, TETRAN having a pumping function for discharging an anticancer agent to cancer cells A screening method characterized by transducing a gene, culturing the transduced cancer cell together with an anticancer agent or an anticancer agent sensitivity enhancer, and evaluating the inhibition of the anticancer drug excretion by detecting the survival rate of the cell. . [Selection] Figure 1 |
priorityDate | 2004-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.