http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005198546-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_264627c9d405ca3e91c884db5fc908ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5e7a9f9b6aa26ac3a15dfb7b4c82bc2 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate | 2004-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e51da433d9a150d5c6c010221265bf8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_935bc464acc57cf101c16f552b8f5d5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3dc215ecb5cfa2e2c3f0ad8863d3d8ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_571b890c86be60206507df715e4573e4 |
publicationDate | 2005-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2005198546-A |
titleOfInvention | Vector incorporating a reporter gene |
abstract | [PROBLEMS] A conventional system using a reporter gene such as luciferase or GFP can monitor gene expression in a small animal or body surface, but monitoring of gene expression in the deep body has insufficient detection sensitivity and quantitativeness. Therefore, it has been desired to develop a monitoring system for gene expression that is difficult, excellent in safety and quantification, and applicable to the human body. As a combination of a reporter gene and a PET tracer for detecting the reporter gene, an estrogen or an estrogen labeled with F-18 having affinity for the estrogen receptor ligand binding region using the ligand binding region of the wild type and mutant estrogen receptor as a reporter The above-mentioned problems have been solved by non-invasively monitoring the expression of a target gene in vivo using an agonist or antagonist as a tracer. [Selection figure] None |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9499797-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9714433-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011519546-A |
priorityDate | 2004-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 341.