| abstract |
The present invention provides nucleic acid and amino acid sequences of novel human tumor associated antigens, ie, apoptosis factor (PDAF) derived from placenta, as well as the use of these sequences in the treatment of diseases associated with immunity and cell proliferation. A PDAF containing a specific amino acid sequence and a biological functional equivalent thereof, a nucleic acid encoding a polypeptide represented by the specific amino acid sequence, and a degenerate sequence are provided. Since it is used for treatment of proliferation or inhibition of immune response, it is a drug used for various routes such as oral and intravenous. [Selection figure] None |