abstract |
[Objective] Obesity and obesity-induced hyperlipidemia, fatty liver and impaired glucose tolerance, diabetes, diabetic complications (diabetic peripheral neuropathy, diabetic nephropathy, diabetes To provide an inhibitor of ACC activity inhibition effective in the treatment of retinopathy, diabetic macroangiopathy, etc.), hypertension and arteriosclerosis. An N-alkylsulfonyl-substituted amide derivative represented by the following formula, an analog thereof or a pharmaceutically acceptable salt thereof has an effective ACC activity inhibitory action. [Chemical 1] |