http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005162734-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79e2ba0c1c69d66370a85141510b892d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 |
| filingDate | 2004-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b1ad4c3ae9f9773ace45629caa2f4dc |
| publicationDate | 2005-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2005162734-A |
| titleOfInvention | Disulfide cross-linked glycoprotein hormone analogs and their preparation and use |
| abstract | 【Task】 Pharmaceutical compositions comprising glycoprotein hormone analogs having improved stability while retaining at least a portion of the biological activity of the corresponding glycoprotein are provided. [Solution] Human Chorionic Gonadotropin (hCG), Human Luteinizing Hormone (hLH), Human Follicle Stimulating Hormone (hFSH), Human Thyroid Stimulating Hormone (hTSH), and Their Functional Mutations Having α-Subunit and β-Subunit A glycoprotein hormone selected from the group consisting of a body, wherein the amino acid sequence is modified to create a disulfide bond between the cysteine of the α-subunit and the cysteine of the β-subunit; An effective amount of the glycoprotein hormone that is exposed between the two residues at the natural cysteine residue position of the glycoprotein hormone and not outside the outermost cysteine unit of the corresponding natural cysteine, and pharmaceutically A pharmaceutical composition comprising an acceptable excipient. [Selection] Figure 1 |
| priorityDate | 1997-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.