| abstract |
PROBLEM TO BE SOLVED: To provide a less astringent composition having a high anti-inflammatory effect on gingival inflammation and an excellent periodontal disease prevention / treatment effect against periodontal disease induced by periodontopathic bacteria forming a biofilm. Offer. SOLUTION: Polyphenol and the following formula (1) [Chemical 1] (In the formula, R 1 represents a hydrogen atom or a hydroxyl group, and R 2 , R 3 , R 4 and R 5 are the same or different and each represents a hydrogen atom, a hydroxyl group, an alkyl group having 1 to 10 carbon atoms, or a group having 1 to 10 carbon atoms. A composition for preventing or treating periodontal disease comprising a lignan represented by a hydroxyalkyl group or an alkoxy group having 1 to 10 carbon atoms) or a plant extract containing the lignan. [Selection figure] None |