| abstract |
Provided are nucleic acids encoding human metabotropic glutamate receptor protein subtypes 2 and 5, and proteins encoded thereby. Encoding the subtypes of human metabotropic glutamate receptors mGluR2 and mGluR5. In addition to being useful for the production of metabotropic glutamate receptor subtypes, these nucleic acids are also useful as probes, so one skilled in the art can identify and isolate relevant receptor subunits without undue experimentation. Is possible. In addition to disclosing novel metabotropic glutamate receptor protein subtypes, compounds that affect the function of such receptors (eg, agonists, antagonists, and modulators (activity modulators) of glutamate receptor function) Use of such receptor subtypes to identify and characterize [Selection figure] None |