| abstract |
PROBLEM TO BE SOLVED: To provide a therapeutic means for a disorder in which T cells are involved or recruited. The present invention relates to peptides that act on T cells, possibly by acting on T cell antigen receptors. The invention further relates to the treatment of various inflammatory and autoimmune disease states involving the use of this peptide. In particular, the peptides are useful for the treatment of disorders in which T cells are involved or recruited. The peptide has the formula: ABCDE (wherein A is absent or 1 or 2 hydrophobic amino acids, B is a positively charged amino acid, C is a peptide consisting of 3-5 hydrophobic amino acids, D is A positively charged amino acid, and E is absent or no more than 8 hydrophobic amino acids). [Selection figure] None |