http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005137333-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9019c0ce5cb7b82c85e121f6cac86dce |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0276 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2003-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b8ecf88d3cf27ef4c662207973d1223 |
publicationDate | 2005-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2005137333-A |
titleOfInvention | Screening method using TBK1 knockout mouse |
abstract | PROBLEM TO BE SOLVED: To provide a screening method for an induction promoter of an antiviral protein such as IFN-β against LPS stimulation or viral infection using TBK1 knockout mouse or a tissue or cell derived from the knockout mouse. A mouse in which part or all of the TANK-binding kinase 1 (TBK1) gene on the chromosome is deleted and the function of expressing TBK1 expressed in the wild type is lost, or a tissue or cell derived from the mouse And a test substance and a ligand recognized by TLR4 or a content thereof, and the like, IFN-β for the ligand recognized by TLR4 or the content thereof in the mouse or a tissue or cell derived from the mouse. The degree of induction of antiviral protein is measured and evaluated, and a substance that promotes response to LPS stimulation or viral infection is screened. |
priorityDate | 2003-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 670.