http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005126422-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 |
filingDate | 2004-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94ce9172b5d86a909a510205a5b68e6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44cc6dd9445953a248800d868d28decb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5b87162d23812cdb2a25642b42fa061 |
publicationDate | 2005-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2005126422-A |
titleOfInvention | Composition for promoting and / or suppressing decrease in collagen accumulation containing triazinoindoleamine compound and the compound or a pharmaceutically acceptable salt thereof as an active ingredient |
abstract | 【Task】 To develop and provide a drug that improves a disease or tissue condition accompanied by a decrease in the amount of collagen in the tissue. [Solution] 1. Formula (I) [Chemical 1] A triazinoindoleamine compound represented by formula (hereinafter referred to as the present compound (I)) and the present compound (I) or a pharmaceutically acceptable salt thereof, Or a composition for suppressing decrease (hereinafter referred to as the present composition); 2. Use of the compound (I) of the present invention or a pharmaceutically acceptable salt thereof for promoting transcription of a type I collagen gene and suppressing transcription of a matrix metalloproteinase-1 (MMP-1) gene; 3. It comprises the step of administering an effective amount of the compound (I) of the present invention or a pharmaceutically acceptable salt thereof to a mammal that can be diagnosed with a disease or tissue condition accompanied by a decrease in the amount of collagen in the tissue. A method for promoting accumulation and / or suppressing decrease in the amount of collagen in the tissue; Etc. are provided. [Selection figure] None |
priorityDate | 2003-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 284.