http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005120014-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d24321bed2edef57b40e064ce34f0a6e |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B51-00 |
| filingDate | 2003-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbb1dd57a44e3bcbd8894492ef43c2a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_897ffb12df84893f2b6901b0e1663daa |
| publicationDate | 2005-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2005120014-A |
| titleOfInvention | Process for producing arylmethylpiperazine derivatives |
| abstract | The present invention provides a means for efficiently producing an arylmethylpiperazine derivative by arylmethylating a piperazine derivative. A piperazine derivative represented by the general formula (1) is arylmethylated to give a general formula (2) [Chemical 1] Wherein R 1 , R 2 , R 3 and R 4 may be the same or different, i) a hydrogen atom, ii) an alkyl group having 1 to 4 carbon atoms, and iii) 1 to 4 carbon atoms. Iv) a halogen group, v) a carboxyl group, vi) a carbamoyl group, vii) an N-alkylcarbamoyl group having 1 to 4 carbon atoms in the alkyl group, R 1 , R 2 , R 3 Except when all of R 4 are hydrogen atoms. In the formula, R 5 , R 6 and R 7 may be the same or different and each represents an aromatic substituent or a hydrogen atom, but at least two of them are aromatic substituents. In the production of the arylmethyl-substituted piperazine derivative represented by (II), a secondary or tertiary alcohol is used as a reaction solvent. [Selection figure] None |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016021524-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016037495-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105992760-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9994530-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022175384-A1 |
| priorityDate | 2003-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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